Inactive Ingredients

The Health business of Lubrizol Life Science (LLS Health) manufactures high performance Carbopol® polymers and Noveon® polycarbophil, which have been used extensively in oral care applications for decades. Initially used in aqueous toothpaste formulations as a thickener and co-binder, Carbopol polymers are now preferred thickeners for anhydrous toothpaste formulations. They are also used in a variety of other toothpaste, mouth rinse, and denture adhesive products. LLS Health additionally manufactures tetraacetylethylenediamine (TAED) as a bleach activator for denture cleaners to prevent bacterial build-up.

Table 1. Lubrizol Ingredients Suitable for Use in Oral Care & Their Applications

Product Trade Name Aqueous Toothpaste Anhydrous Toothpaste Mucoadhesive Applications
Denture Fixative  Denture Cleaner
Carbopol® 971P NF Polymer

Carbopol® 974P NF Polymer  
Carbopol® ETD 2020 NF Polymer

Carbopol® 980 NF Polymer
Carbopol® 956 Polymer
Noveon® AA1 Polycarbophil USP

Carbopol polymers and Noveon polycarbophil ingredients are utilized in oral care products as:

  • Rheology modifiers
  • Binders
  • Suspension stabilizers
  • Mucoadhesive aids

There are multiple grades of Carbopol polymers, each for specific applications and with slight chemical differences to provide various benefits. Products within the Carbopol polymer family are chemically similar in that they are all high molecular weight, crosslinked polyacrylic acid polymers. Noveon® AA-1 Polycarbophil USP is also a high molecular weight acrylic acid polymer but has a different crosslinking agent than Carbopol polymers. See Table 1 for our available polymer grades and their applicable dosage forms. 

Our Carbopol and Noveon multifunctional polymers are:

  • Highly efficient thickeners/co-binders enabling excellent formulation characteristics at low usage levels
  • The preferred thickener for anhydrous compositions
  • Excellent mucoadhesive polymers, which protect and lubricate the mucosa as well as allow for prolonged active and flavor retention
  • Ideal for enabling formulations that exhibit reduced stringiness, a significant advantage when using high-speed tube-filling machines
  • Synergistic co-thickeners with either cellulosic polymers or natural gums, for improved economics and formulations
  • Optimal for providing enhanced aesthetics, such as toothpaste ribbon stand-up and high clarity gels
  • Consistent from lot-to-lot due to their synthetic nature
  • Able to be processed by cold processing
  • Synthetic polymers with a lower bioburden that do not support microbial growth when compared to natural cellulosic polymers and gums
  • Compliant with global pharmacopeial and regulatory requirements, possessing a long history of product quality, safety, and reproducibility