This webinar describes the history, CMC aspects and potential applications of nanoparticle suspensions (NSs). This drug delivery technology should be considered for crystalline, sparingly water-soluble APIs. The presentation highlights applications for sterile products. It may be a viable option to enable IV administration of insoluble APIs and may also be used for long-acting injectables when the nanoparticle suspensions are dosed via IM or SC injection.