Posted by Ashley Rezak | 04/25/2024
In recent years, the landscape of pharmaceutical formulations has been witnessing a significant shift towards non-invasive delivery methods. Among these, nasal administration has emerged as a promising option, particularly in the wake of a respiratory virus pandemic and the quest for innovative drug delivery solutions. With a growing interest in nasal drug delivery, there's also a corresponding surge in products aiming to protect against respiratory infections.
Posted by Nicholas DiFranco | 04/17/2024
Oral suspensions are pharmaceutical formulations in which solid particles of active ingredients are dispersed in a liquid vehicle. These suspensions are commonly used for administering medications to patients who have difficulty swallowing solid dosage forms, such as tablets or capsules, or for those who require customized dosages. Here's a comprehensive guide to understanding and formulating oral suspensions:
Posted by Ashley Rezak | 01/18/2024
Topical drug delivery has long been a significant route of treatment for various ailments. Ranging from simple salves used by ancient civilizations to the sophisticated formulations of today, the progress in this sector represents the confluence of biology, chemistry, and innovative technology. But the role of a drug isn't just about its therapeutic effect. The medium through which it's delivered – the excipients – play an indispensable role in dictating the efficacy, stability, and overall performance of a topical product.
Posted by Nicholas DiFranco | 08/30/2023
Extended-release tablets, also known as sustained-release, controlled-release, or time-release tablets, have become increasingly important in the healthcare sector due to their ability to maintain consistent drug levels in the body over a specific period. This drug delivery system provides various benefits, including enhanced patient compliance, minimized side effects, and improved therapeutic efficacy.
Posted by Ashley Rezak | 08/23/2023
While advancements in drug delivery are continually improving drug efficacy and bioavailability, there are still significant areas of unmet need in the market. This post discusses some key challenges of oral drug formulations and why they are important to address for patient health and differentiation in a crowded market. We uncover strategies for overcoming these challenges, including extended drug release, taste masking, and tablet size reduction.
Posted by Ashley Rezak | 08/01/2023
Topical drug delivery is a desirable option for formulators seeking a non-invasive, patient-preferred route of administration.
Posted by Joey Glassco | 06/29/2023
It’s no secret that solubility and bioavailability issues continue to challenge formulators and drug developers.
Posted by LLS Health Technical Team | 03/17/2023
The FDA 505(b)(2) regulatory pathway for drug approval, which allows applicants to use existing safety data as evidence, continues to grow in popularity.
Posted by Nicholas DiFranco | 01/25/2023
For drug developers working on oral solid dosage drug projects, solubility, and therefore bioavailability, is a significant challenge. At present, poor water solubility impacts around 40% of drugs currently on the market.
Posted by LLS Health Technical Team | 05/03/2022
Apisolex™ technology provides formulators with a safe, polyamino-acid-based excipient to enhance the solubility of BCS Class II and IV APIs, including oncology agents, for parenteral delivery.
