Carbopol® 941 NF Polymer

Applicable synonyms for Carbopol® 941 NF Polymer: carbomer, carboxypolymethylene 
Polymerization/Residual solvent: Benzene

Key features: 

• Thickener/rheology modifier

Additional features:

• Bioadhesive agent
• Suspension & emulsion stabilizer

Recommended for use in the following dosage forms:

• Semisolids & gels

Recommended for use in the following markets / routes of administration:

• Topical drug delivery

Carbopol® 941 NF polymer meets the limits cited in the current edition of the following monographs: 

• United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer 941
• Japanese Pharmaceutical Excipients (JPE) Monograph for Carboxyvinyl Polymer

Usage levels: 

• Topical: 0.5-3 wt%

Note on toxicity testing:

The toxicity of carbomers has been summarized by the Cosmetic Ingredient Review Expert Panel in their assessment of the safety of the carbomers for cosmetic ingredients. This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol 941 NF polymer. Bulletin 2 provides a summary of all toxicology studies for Lubrizol’s pharmaceutical grade polymers.

Additionally, Lubrizol has filed a Type V DMF with FDA. A letter of authorization (LOA) can be issued for FDA drug applications.